骨桥蛋白在关节疾病中的表达及其意义
熊依林;孙金鹏;雷光华;
摘要(Abstract):
<正>骨桥蛋白(osteopontin,OPN)是一种多功能的细胞外基质蛋白,因最初作为骨组织中一种非胶原基质蛋白被发现而得名[1]。OPN可以广泛参与多种生理和病理过程,包括炎症反应、免疫调节、组织修复、骨的发生发育和重建及肿瘤等[2~5]。同时,多种类型细胞如破骨细胞、软骨细胞、滑膜细胞、内皮细胞及
关键词(KeyWords): 骨桥蛋白;类风湿性关节炎;骨关节炎
基金项目(Foundation):
作者(Author): 熊依林;孙金鹏;雷光华;
Email:
DOI:
参考文献(References):
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