苏帆;张宁峰;刘有静;邓桢翰;许鉴;陈康;朱伟民;

• 1:安徽医科大学深圳二院临床医学院
• 2:深圳市第二人民医院

摘要(Abstract)：

[目的]介绍全关节镜下自体软骨细胞移植修复膝软骨缺损的技术及疗效。[方法]选取2016年8月～2018年8月,共有22例膝软骨缺损患者,初次手术取患膝非负重区软骨体外培养、扩增并与胶原纤维支架复合,3周后接受自体软骨细胞移植,全程均在关节镜下进行。术后3、6、12个月随访。[结果]所有患者手术顺利,无严重并发症发生。与术前相比较,术后12个月VAS评分显著降低[(5.36±0.95) vs(0.32±0.48),P<0.001],Lysholm评分显著增加[(59.18±4.92) vs(90.64±1.84),P<0.001]。术后12个月T2 Mapping核磁Z值较术初显著改善[(0.42±0.06) vs(0.89±0.08),P<0.001]。[结论]全关节镜下自体软骨细胞移植修复膝关节缺损可以迅速改善症状,无严重并发症。

关键词(KeyWords)： 软骨缺损;全关节镜技术;自体细胞软骨移植

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金资助项目（编号：81672234）;; 深圳市协同创新计划项目（编号：GJHZ20180416164801042）;; 深圳市科技计划项目（编号：201606018）

作者(Author): 苏帆;张宁峰;刘有静;邓桢翰;许鉴;陈康;朱伟民;

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