成骨细胞对人工关节金属磨损微粒的体外生物学反应
蔡贤华;陈安民;陈庄洪;
摘要(Abstract)：
关键词(KeyWords)：
基金项目(Foundation):
作者(Author): 蔡贤华;陈安民;陈庄洪;
Email:
DOI:
参考文献(References)：
- (1)W ooley PH,Schwarz EM.Aseptic loosen ing[J].Gene Ther,2004,11(4):402-407.
- (2)Goodman SB,Trindade M,Ma T,et al.Pharmacologic modu lation ofperiprosthetic osteolysis[J].C lin O rthop,2005,(430):39-45.
- (3)Verm es C,Chandrasekaran R,Jacobs JJ,et al.The effects of particu-late wear debris,cytok ines,and growth factors on the functions ofMG-63 osteob lasts[J].J Bone Joint Surg(Am),2001,83(2):201-211.
- (4)W angML,Tu ll R,Manner PA,et al.D irect and ind irect induction ofapoptosis in human m esenchymal stem cells in response to titan iumparticles[J].J O rthop Res,2003,21(4):697-707.
- (5)W angML,Sharkey PF,Tuan RS.Particle b ioreactivity and wear-m ed i-ated osteolysis[J].J Arthroplasty,2004,19(8):1028-1038.
- (6)Campbell PA,W ang M,Am stutz HC,et al.Positive cytok ine produc-tion in failed m etal-on-m etal total h ip replacem ents[J].Acta O rthopScand,2002,73(5):506-512.
- (7)C rotti TN,Sm ith MD,F ind lay DM,et al.Factors regu lating osteoclastformation in human tissues ad jacent to peri-implant bone loss:expres-sion of receptor activator NFκB,RANK ligand and osteoprotegerin[J].B iomaterials,2004,25(4):565-573.
- (8)Lohmann CH,D ean DD,Koster G,et al.Ceram ic and PMMA particlesd ifferentially affect osteob last phenotype[J].B iomaterials,2002,23(8):1855-1863.
- (9)G iant TT,Jacobs JJ,M ikecz K,et al.Particu late-induced,prostaglan-d in-and cytok ine-m ed iated bone resorption in an experim ental systemand in failed joint replacem ents[J].Am J Ther,1996,3(1):27-41.
- (10)MaloneyW J,Sm ith RL,Schmalzried TP,et al.Isolation and character-ization ofwear particles generated in patientswho have had failure of ah ip arthroplasty w ithout cem ent[J].J Bone Joint Surg(Am),1995,77(9):1301-1310.
- (11)A llen M J,Myer BJ,M illett PJ,et al.The effects of particu late cobalt,chrom ium,and cobalt-chrom ium alloy on human osteob last-like cellsin vitro[J].J Bone Joint Surg(B r),1997,79(3):475-482.
- (12)Roebuck KA,Verm es C,Carpenter LR,et al.Down-regu lation of pro-collagen alphal[Ⅰ]m essenger RNA by titan ium particles correlatesw ith nuclear factor kappaB(NF-kappaB)activation and increased relA and NF-kappaB 1 b ind ing to the collagen promoter[J].J BoneM in-er Res,2001,16(3):501-510.
- (13)Kuroda S,Takeda S,Nakamura M.E ffects of six particu late m etals onosteob last-like MG-63 and HOS cells in vitro[J].D entMater J,2003,22(4):507-520.
- (14)Yao JL,Cs-Szabo G,Jacobs JJ,et al.Suppression of osteob last functionby titan ium particles[J].J Bone Joint Surg(Am),1997,79(1):107-112.
- (15)Kuroda S,Takeda S,Nakamura M.E ffects of six particu late m etals onosteob last-like MG-63 and HOS cells in vitro[J].D entMater J,2003,22(4):507-520.
- (16)Fritz E A,G iantTT,Verm es C,et al.Titan ium particles induce the im-m ed iate early stress responsive chemok ines IL-8 and MCP-1 in osteo-b lasts[J].J O rthop Res,2002,20(3):490-498.
- (17)D ean DD,Schwartz Z,L iu Y,et al.The effect of u ltra-h igh molecu larweight polyethylene wear debris on MG63 osteosarcoma cells in vitro[J].J Bone Joint Surg(Am),1999,81(4):452-461.
- (18)Lohmann CH,Schwartz Z.,KosterG,et al.Phagocytosis ofwear debrisby osteob lasts affects d ifferentiation and local factor production in amanner dependent on particle composition[J].B iomaterials,2000,21(6):551-561.
- (19)Kwon SY,TakeiH,P iolletti DP,et al.Titan ium particles inh ib it osteo-b last adhesion to fibronectin-coated substrates[J].J O rthop Res,2000,18(2):203.
- (20)P ioletti DP,Takei H,Kwon SY,et al.The cytotoxic effect of titan iumparticles phagocytosed by osteob lasts[J].J B iom ed Mater Res,1999,46(3):399-407.
- (21)O Connor DT,ChoiMG,Kwon SY,et al.New insight into the m echa-n ism of h ip prosthesis loosen ing:effect of titan ium debris size on osteo-b last function[J].J O rthop Res,2004,22(2):229-236.
- (22)Heinemann DE Lohmann C,S iggetkow H,et al.Human osteob last-likecells phagocytose m etal particles and express the macrophage markerCD68 in vitro[J].J Bone Joint Surg(B t),2000,82(2):283-289.
- (23)Kwon SY,L in T,TakeiH,et al.A lterations in the adhesion behavior ofosteob lasts by titan ium particle load ing:inh ib ition of cell function andgene expression[J].B iorheology,2001,38(2~3):161-183.
- (24)Verm es C,Roebuck KA,Chandrasekaran R,et al.Particu late weardebris activates protein tyrosine k inases and nuclear factor kB,wh ichdown-regu lates typeⅠcollagen synthsis ob lasts in human osteob lasts[J].J Bone M iner Res,2000,15(9):1756-1765.
- (25)Lhotka C,Szekeres T,Steffan I,et al.Four-year study of cobalt andchrom ium blood levels in patientsmanaged w ith two d ifferentmetal-on-metal total hip replacements[J].J Orthop Res,2003,21(2):189-195.
- (26)Hallab NJ,Verm es C,M essina C,et al.Concentration-and composi-tion-dependent effects ofm etalions on human MG-63 osteob lasts[J].J B iom ed Mater Res,2002,60(3):420-433.
- (27)An issian L,Stark A,Dah istrand H,et al.Cobaltions influence proliferation and function of human osteob last-like cells[J].Acta O rthopScand,2002,73(3):369-374.
- (28)Sun ZL,W ataha JC,Hanks CT.E ffects ofm etalions on osteob last-likecellm etabolism and d ifferentiation[J].J B iom ed Mater Res,1997,34(1):29-37.