苏晴晴;张子安;王田田;房晓;李涛;吴晓淋;陈伯华;李海燕;

• 1:青岛大学附属医院骨科
• 2:青岛大学护理学院

摘要(Abstract)：

[目的]探讨微创与传统全膝关节置换术(TKA)对膝骨关节炎(KOA)患者术后早期骨代谢指标的影响。[方法] 2019年1月～2019年12月行单侧TKA的90例KOA患者纳入本研究,随机分为两组。其中,45例行微创TKA (微创组),45例行传统TKA (传统组)。比较两组早期临床结果、骨代谢检测与骨密度检查结果。[结果]两组患者均顺利手术,无严重并发症,微创组术后24 h内VAS评分显著小于传统组(P<0.05)。两组患者间术前1 d的β-CTX、P1NP、TRACP5b和BGP的差异均无统计学意义(P>0.05),两组患者上述指标术后3 d上升至峰值,而后持续下降,不同时间点差异均有统计学意义(P<0.05)。术后3～30 d,微创组的β-CTX、P1NP、TRACP5b和BGP均显著低于传统组,各时间点两组间差异均有统计学意义(P<0.05)。手术前后两组的BMD-AKJ值均无明显变化(P>0.05),相应时间点,两组间BMD-AKJ值的差异均无统计学意义(P>0.05)。[结论]微创TKA术后早期骨代谢水平低于传统TKA。

关键词(KeyWords)： 微创手术;全膝关节置换术;骨代谢;骨重建

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金资助项目(编号：81802151);; 青岛大学医学部“临床医学+X”面上项目(编号：20181018)

作者(Author): 苏晴晴;张子安;王田田;房晓;李涛;吴晓淋;陈伯华;李海燕;

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