龙厚清;陈文立;徐晶辉;谢文翰;黄阳亮;刘少喻;李佛保;

• 1:中山大学附属第一医院脊柱外科
• 2:中山大学附属第一医院神经外科

摘要(Abstract)：

[目的]观察围手术期使用神经妥乐平对颈椎后路术后轴性痛的预防作用和近期疗效。[方法]2012年3月~2013年3月间,将颈椎后路手术患者随机分为治疗组(神经妥乐平组,n=62)和对照组(Vit-B12组,n=58)。术前1 d用药,连续应用至术后7 d。比较两组轴性痛发生率、疼痛模拟视觉评分(VAS)、日本骨科学会(JOA)、生活质量评分(QOL)差异。MRI测量比较两组颈后伸肌群肌萎缩程度(MAD)。[结果]术后早期轴性痛发生率两组无显著性差异(P>0.05),4、12周治疗组轴性痛发生率显著低于对照组(P<0.05),术后3 d两组平均疼痛水平无统计学差异,术后4、12周治疗组平均疼痛水平明显低于对照组(P<0.05)。两组术后JOA评分及恢复率差异无统计学意义(P>0.05)。治疗组术后12周QOL显著优于对照组(P<0.05),治疗组颈后伸肌群MAD明显小于对照组(P<0.05)。[结论]围手术期使用神经妥乐平可减轻颈椎后路手术后颈后深肌群萎缩,预防轴性痛发生。

关键词(KeyWords)： 轴性痛;神经妥乐平;颈椎后路手术

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 龙厚清;陈文立;徐晶辉;谢文翰;黄阳亮;刘少喻;李佛保;

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参考文献(References)：

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