马尾神经沉降征在腰椎管狭窄症诊疗中的意义Significance of cauda equina nerve root sedimentation sign in lumbar spinal stenosis
岳茂兴;西永明;
摘要(Abstract):
[目的]探讨马尾神经沉降征(NRSS)在腰椎管狭窄症(LSS)治疗中的意义。[方法]回顾性分析本院2017年3月~2018年3月98例LSS患者行TLIF术的临床资料,根据MRI下马尾神经形态学分型判定马尾神经是否沉降将所有患者分为阳性组和阴性组,比较两组一般资料、Oswestry残障指数(ODI)和疼痛视觉模拟评分(VAS)及Macnab疗效评级,采用多元逻辑回归分析NRSS的主要影响因素。[结果]在98例LSS患者中,NRSS阳性者79例,占80.61%;NRSS阴性者19例,占19.39%。NRSS阳性与阴性两组比较在性别、年龄、体重、病程以及手术节段的差异无统计学意义(P>0.05)。两组患者间术前ODI评分差异不具有统计学意义(P>0.05);但是,术后3、6个月时,NRSS阳性组的ODI评分显著低于NRSS阴性组,差异均具有统计学意义(P<0.05)。两组患者术前和手术后各时间点VAS评分差异均无统计学意义(P>0.05)。术后6个月Macnab疗效评级阳性组显著优于阴性组(P<0.05)。逻辑回归结果表明,NRSS征主要影响术后3个月ODI评分,术后6个月ODI评分和术后6个月Macnab评级(P<0.05);而对其他因素无影响(P>0.05)。[结论] NRSS阳性常见于LSS患者中,且NRSS阳性者的手术疗效优于阴性者,NRSS可能是预估手术效果的指标。
关键词(KeyWords): 马尾神经沉降征;腰椎管狭窄症;经孔椎体间融合术
基金项目(Foundation):
作者(Author): 岳茂兴;西永明;
Email:
DOI:
参考文献(References):
- [1] Barz C, Melloh M, Staub LP, et al. Reversibility of nerve root sedimentation sign in lumbar spinal stenosis patients after decompression surgery[J]. Eur Spine J, 2017, 26(10):2573-2580.
- [2] Verbiest H. A radicular syndrome from developmental narrowing of the lumbar vertebral canal. 1954[J]. Clin Orthop, 2001,(384):3-9.
- [3]敖鹏,吴添龙,张磊磊,等.神经根沉降征在腰椎管狭窄症术前术后的比较性研究[J].中国矫形外科杂志, 2016, 24(19):1735-1739.
- [4]陈延超,余作冲,曹蓉,等. MRI显示神经根沉降征在腰椎管狭窄症中的应用价值[J].中国组织工程研究, 2017, 21(31):5042-5047.
- [5] Barz T, Melloh M, Staub LP, et al. Nerve root sedimentation sign:evaluation of a new radiological sign in lumbar spinal stenosis[J].Spine, 2010, 35(8):892-897.
- [6] Piechota M, Król R, Elias DA, et al. The nerve root sedimentation sign in diagnosis of lumbar spinal stenosis[J]. Acta Radiol, 2019,60(5):634-642.
- [7] Barz T, Staub LP, Melloh M, et al. Clinical validity of the nerve root sedimentation sign in patients with suspected lumbar spinal stenosis[J]. Spine J, 2014, 14(4):667-674.
- [8]许鹏,史建刚,叶晓健,等.伴马尾神经沉降征阳性腰椎管狭窄症患者的手术疗效观察[J].中国医药导报, 2016, 13(15):96-99.
- [9]黄志豪,谢志阳,吴小涛.神经根沉降征在腰椎管狭窄症中的研究进展[J].中国修复重建外科杂志, 2019, 33(7):795-800.
- [10]刘万祥,黄民锋,陈远明,等.侧路椎间孔镜技术治疗腰椎管狭窄症的有效性和安全性[J].中国医药, 2019, 14(3):412-415.
- [11] Chen J, Wang J, Wang B, et al. Post-surgical functional recovery,lumbar lordosis, and range of motion associated with MR-detectable redundant nerve roots in lumbar spinal stenosis[J]. Clin Neurol Neurosurg, 2016, 140(1):79-84.
- [12] Sirvanci M, Bhatia M, Ganiyusufoglu KA, et al. Degenerative lumbar spinal stenosis:correlation with Oswestry Disability Index and MR Imaging[J]. Eur Spine J, 2008, 17(5):679-685.
- [13] Burgstaller JM, Schüffler PJ, Buhmann JM, et al. Is There an association between pain and magnetic resonance imaging parameters in patients with lumbar spinal stenosis[J]. Spine, 2016, 41(17):1053-1062.
- [14] Madsen R, Jensen TS, Pope M, et al. The Effect of body position and axial load on spinal canal morphology:an MRI study of central spinal stenosis[J]. Spine, 2008, 33(1):61-67.
- [15] Barz T, Melloh M, Staub LP, et al. Increased intraoperative epidural pressure in lumbar spinal stenosis patients with a positive nerve root sedimentation sign[J]. Eur Spine J, 2014, 23(5):985-990.
- [16]周孝文,姜宏.神经根沉降征在腰椎管狭窄症诊疗中的意义[J].颈腰痛杂志, 2016, 37(1):64-67.
- [17] Moses RA, Zhao W, Staub LP et al. Is the sedimentation sign associated with spinal stenosis surgical treatment effect in SPORT[J].Spine, 2015, 40(3):129-136.
- [18]王辉,喻亮,冯华明.经皮椎间孔路径下内镜治疗中央型腰椎管狭窄症的疗效分析[J].局解手术学杂志, 2020, 29(1):43-46.