带血供腓骨移植重建股骨近端溶骨性病变致骨缺损Surgical treatment of invasive benign tumors and tumor- like lesions of the proximal femur
高明暄;李旭升;付晓燕;陈彦飞;赵锟;常彦峰;李生贵;邵宏斌;
摘要(Abstract):
[目的]评价带血供游离腓骨移植重建股骨近端侵袭性良性溶骨性病变所致骨缺损的临床疗效。[方法]总结自2008年4月~2013年3月收治股骨近端良性侵袭性肿瘤或肿瘤样病变共14例,采用病灶内扩大刮除、氯化锌烧灼瘤壁,吻合血管腓骨移植,支持钢板内固定等方法手术治疗,影像学随访评价病变转归、植骨愈合;采用改良肌肉骨髂系统肿瘤学会(Musculoskeletal Tumor Society,MSTS)肢体功能评价表随访肿瘤切除术后患者肢体功能。[结果]随访18~67个月,平均(35.71±15.80)个月。其中1例骨巨细胞瘤患者于术后12个月复发。其余13例患者随访期间均未见病变复发表现,钢板固定无松动、断裂,无术后病理性骨折,未见股骨头缺血性坏死等其他并发症。移植腓骨无缺血坏死表现、与受区2~7个月骨性愈合,平均愈合时间(4.54±1.27)个月。术后3、6个月MSTS功能评分依次为(25.57±4.27),(27.07±6.53)分。[结论]病灶刮除,氯化锌烧灼瘤壁,吻合血管腓骨移植填充重建,结合支持钢板内固定是股骨近端侵袭性良性肿瘤及瘤样病变的有效外科治疗方法。中期随访表现为病变复发率低,破坏骨结构得以重建,髋关节功能良好。
关键词(KeyWords): 游离带血供腓骨;侵袭性良性骨肿瘤;瘤样病变;病灶刮除;氯化锌;股骨近端
基金项目(Foundation): 甘肃省自然科学基金面上项目(编号:1308RJZA210);; 中国博士后科学基金面上项目(编号:2013M542571)
作者(Author): 高明暄;李旭升;付晓燕;陈彦飞;赵锟;常彦峰;李生贵;邵宏斌;
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DOI:
参考文献(References):
- [1]Kundu ZS,Gogna P,Sangwan SS,et al.Benign lytic lesions of the femoral neck:mid-term results of extended curettage and sartorius muscle pedicle bone grafting[J].Arch Orthop Trauma Surg,2013,133(4):457-462.
- [2]George B,Abudu A,Grimer RJ,et al.The treatment of benign lesions of the proximal femur with non-vascularised autologous fibular strut grafts[J].J Bone Joint Surg Br,2008,90(5):648-651.
- [3]Kushare IV,Colo D,Bakhshi H,et al.Fibrous dysplasia of the proximal femur:surgical management options and outcomes[J].J Child Orthop,2014,8(6):505-511.
- [4]高秋明,张宇,厉孟,等.吻合血管腓骨移植修复儿童股骨近端复发性骨囊肿[J].骨科,2014,5(1):26-28.
- [5]Moon MS,Kim SS,Moon JL,et al.Treating giant cell tumours with curettage,electrocautery,burring,phenol irrigation,and cementation[J].J Orthop Surg(Hong Kong),2013,21(2):209-212.
- [6]Taylor GI,Miller GD,Ham FJ.The free vascularized bone graft.A clinical extension of microvascular techniques[J].Plast Reconstr Surg,1975,55(5):533-544.
- [7]Korompilias AV,Paschos NK,Lykissas MG,et al.Recent updates of surgical techniques and applications of free vascularized fibular graft in extremity and trunk reconstruction[J].Microsurgery,2011,31(3):171-175.
- [8]赵国红,谢振军,孙华伟,等.吻合血管的腓骨移植修复下肢骨缺损的疗效[J].实用临床医学,2014,15(4):58-60.
- [9]Zhen P,Hu YY,Luo ZJ,et al.One-stage treatment and reconstruction of Gustilo type III open tibial shaft fractures with a vascularized fibular osteoseptocutaneous flap graft[J].J Orthop Trauma,2010,24(12):745-751.
- [10]Zhen P,Liu XY,Lu H,et al.Fixation and reconstruction of severe tibial shaft fractures with vascularized fibular grafting[J].Arch Orthop Trauma Surg,2011,131(1):93-99.
- [11]Enneking WF,Dunham W,Gebhardt MC,et al.A system for the functional evaluation of reconstructive procedures after surgical treatment of tumors of the musculoskeletal system[J].Clin Orthop,1993,286:241-246.
- [12]Tanaka K,Maehara H,Kanaya F.Vascularized fibular graft for bone defects after wide resection of musculoskeletal tumors[J].J Orthop Sci,2012,17(2):156-162.
- [13]Prosser GH,Baloch KG,Tillman RM,et al.Does curettage without adjuvant therapy provide low recurrence rates in giant-cell tumors of bone[J].Clin Orthop,2005,435:211-218.
- [14]Xu S,Yu X,Xu M,et al.Inactivated autograft-prosthesis composite has a role for grade III giant cell tumor of bone around the knee[J].BMC Musculoskelet Disord,2013,14:319.
- [15]Campanacci M,Baldini N,Boriani S,et al.Giant-cell tumor of bone[J].J Bone Joint Surg Am,1987,69(1):106-114.
- [16]Han I,Choi ES,Kim HS.Monostotic fibrous dysplasia of the proximal femur:natural history and predisposing factors for disease progression[J].Bone Joint J,2014,96-B(5):673-676.
- [17]Montalti M,Alberghini M,Ruggieri P.Secondary aneurysmal bone cyst in fibrous dysplasia of the proximal femur[J].Orthopedics,2009,32(5):363.
- [18]Malizos KN,Zalavras CG,Soucacos PN,et al.Free vascularized fibular grafts for reconstruction of skeletal defects[J].J Am Acad Orthop Surg,2004,12(5):360-369.
- [19]Enneking WF,Eady JL,Burchardt H.Autogenous cortical bone grafts in the reconstruction of segmental skeletal defects[J].J Bone Joint Surg Am,1980,62(7):1039-1058.
- [20]石若梅,徐家友,张璐.游离腓骨移植修复下颌骨缺损的临床应用[J].中华显微外科杂志,2012,35(3):231-232.
- [21]Sim E,Lang S.Joint salvaging surgery for an extensive giant cell tumor of the proximal femur complicated by a transcervical fracture[J].Arch Orthop Trauma Surg,1997,116(6-7):431-434.
- [22]Sun Y,Zhang C,Jin D,et al.Treatment for large skeletal defects by free vascularized fibular graft combined with locking plate[J].Arch Orthop Trauma Surg,2010,130(4):473-479.