蔡贤华;李振华;王庆;黄卫兵;

• 1:广州军区武汉总医院骨科
• 2:南方医科大学

摘要(Abstract)：

[目的]探讨骨基质明胶颗粒(BMG)复合骨水泥(PMMA)用于人工关节假体固定的可行性。[方法]制备成年新西兰白兔股骨中上段15 mm骨缺损,于髓腔内置入直径3 mm的钛棒并以骨水泥或BMG/PMMA复合材料固定,模拟人工股骨头置换术之动物模型,分别进行术后步态、X线检查、生物力学、组织学检查观察。[结果]术后第2 d～12周两组动物均可正常行走;术后24 h力学检测示两种固定方法无显著性差异;随着时间的延长,骨缺损无短缩;X线及组织学检查示复合材料组钛棒周围有成骨现象,扫描电镜见复合材料内有骨长入。[结论]BMG颗粒/PMMA复合材料固定假体时显示出可靠的力学性能及诱导成骨能力,将可能使其成为一种新的假体固定方法。

关键词(KeyWords)： 骨基质明胶;骨水泥;材料;人工关节;假体固定

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 蔡贤华;李振华;王庆;黄卫兵;

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DOI:

参考文献(References)：

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