护骨素系统与骨质疏松症
张忠荣,王爱民
摘要(Abstract)：
关键词(KeyWords)：
基金项目(Foundation):
作者(Author): 张忠荣,王爱民
Email:
DOI:
参考文献(References)：
- [1] LorenzoJ.Interactionsbetweenimmuneandbonecells:newinsightswithmanyremainingquestions[J].JClinlnvest,2000,106:749～752.
- [2] LiJ,SarosiI,YanXQ ,eta1.RANKistheintrinsichematopoieticcellsurfacereceptorthatcontrolsosteoclastogenesisandregulationofbonemassandcalciummetabolism[J].ProcNatlAcadSciUSA ,2000,97:1566～1571.
- [3] HofbauerLC ,LaceyDL ,DunstanCR ,eta1.Interleukin lbandTu morNecrosisFactor a,ButNotInterleukin6,StimulateOsteoprote gerinLigandGeneExpressioninHumanOsteoblasticCells[J].Bone.l99925(3):255～259.
- [4] YanT ,RiggsBL ,BoyleWJ ,etal.RegulationofosteoclastogenesisandRANKexpressionbyTGF β1[J].JCellBlochem,2000,83:320～325.
- [5] SaikaM ,lnoueD ,KidoS ,etal.17βEstradiolstimulatesexpressionofosteoprotegerinbyamousestromalcellline,ST 2,viaestrogenre ceptorα[J].Endocrinology,2001,142:2205～2212.
- [6] HofbauerLC ,GoriF ,RiggsBL ,eta1.Stimulationofosteoprotegerinligandandinhibitionofosteoprotegerinproductionbyglucocorticoidsinhumanosteoblasticlineagecells:potentialparacrinemechanismsofglucocorticoid inducedosteoporosis[J].Endocrinology,1999,140:4382～4389.
- [7] SugiyamaT .Involvementofinterleukin6andprostaglandinE2inperiarticularosteoporosisofpostmenopausalwomenwithrheumatoidarthritis[J].J BoneMinerMetab,2001,19(2):89～96.
- [8] HofbauerLC ,HeufelderAE .Roleofreceptoractivatorofnuclearfactor kappaBligandandosteOprotegerininbonecellbiology[J].J MolMed,2001,79(56):243～53.
- [9] CaoJ,VentonL ,SakataT ,eta1.ExpressionofRANKLandOPGcorrelateswithage relatedbonelossinmaleC57BL/6mice[J].JBoneMinerRes,2003,18(2):270～7.
- [10]MakhlufHA ,MuellerSM ,MizunoS ,eta1.Agerelateddeclinenost woprotegerinexptessionbyhumanbonemarrowcellsculturedinthreedimensionalcollagensponges[J].JBiochemBiophysRescom mun,2000,268:669～672.
- [11]KostenuikPJ,ShalhoubV .Osteoprotegerin:aphysiologicalandphar macologicalinhibitorofboneresorption[J].CurrPharmDes.2001,7(8):613～635.
- [12]BekkerPJ ,HollowayD ,NakanishiA ,eta1.Theeffectofasingledoseofosteoprotegerininopstmenopausalwomen[J].JBoneMinerRes,2001,16:348～360.
- [13]BolonB .ChristopherC ,MarkD ,etal.,Adenoviraldeliveryofosteo protegerinamelioratesboneresorptioninmouseovariectomymodelofosteoporosis[J].Mol.Ther,2001,(3):197～205.
- [14]MalyankarUM ,ScatenaM ,SuchlandKL ,etal.Osteoprotegerinisanαυβ3 induced,NF кB dependentsurvivalfactorforendothelialcells[J].JBiolChem,2000,275:2095920962.
- [15]KongYY ,FataJE ,LiJ,etal.Theosteoclastdifferentiationfactorosteoprotegerin ligandisessentialformammary glanddevelopment[J].Cell,2000,103:41～50.