魏伟;于占革;

• 1:哈尔滨医科大学附属第一医院骨科

摘要(Abstract)：

<正>1椎间盘生物学和退变椎间盘(intervertebral disc,IVD)是纤维软骨结构,由中央髓核(NP)和周围的纤维环(AF)构成。两个部分由不同细胞分型和细胞外基质构成。髓核细胞是圆形的像软骨细胞一样而纤维环有更多成纤维细胞的狭长的形状。髓核细胞生成的细胞外基质富含蛋白聚糖类(PGs),主要有聚集蛋白聚糖和Ⅱ型胶原。AF细胞可生成大量Ⅰ型胶原但仅有少量的PG或者Ⅱ型胶原。椎间盘是无血管的所以营养成分很难扩散。

关键词(KeyWords)： 组织工程;基因治疗;干细胞;细胞因子

Abstract:

Keywords:

基金项目(Foundation): 黑龙江省攻关课题项目(编号GC06C414)

作者(Author): 魏伟;于占革;

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DOI:

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