基因调控技术在骨组织工程中应用的研究进展Research progress of gene regulation technology in bone tissue engineering
方成;胡永成;陈晓鹏;
摘要(Abstract):
[目的]综述基因调控技术的最新研究进展,全面分析控释技术在骨组织工程中应用。[方法]广泛查阅近几年来国内外关于骨组织工程中基因表达调控的相关文献,并进行综述。[结果]基因调控技术能够严格调节成骨成血管因子表达,可以有效的避免生长因子过度表达,而导致有害的异位骨化或异常骨的形成以及异常血管或肿瘤血管的形成。[结论]生理状态下骨修复重建是多种生长因子在细胞内序贯表达,通过不同基因调控技术模拟生理状态下成血管和成骨因子序贯释放,将为研究血管化组织工程骨提供新策略。
关键词(KeyWords): 骨组织工程;基因调控技术;骨缺损修复
基金项目(Foundation):
作者(Author): 方成;胡永成;陈晓鹏;
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DOI:
参考文献(References):
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