经皮椎体后凸成形术治疗不同时期椎体压缩骨折的疗效分析Effect of percutaneous kyphoplasty for osteoporotic vertebral compression fracture at different stages
刘法敬;申勇;张英泽;丁文元;杨大龙;徐佳欣;任虎;
摘要(Abstract):
[目的]观察经皮椎体后凸成形术治疗不同时期骨质疏松性椎体压缩骨折的临床疗效差异。[方法]回顾性分析2007年1月~2008年8月在本院行经皮椎体后凸成形术治疗的82例单节段骨质疏松性椎体压缩骨折患者,按症状出现到接受手术治疗的时间长短,将其分成3组。急性期组(Ⅰ组):在2周内接受手术治疗的患者,30例。早期修复组(Ⅱ组):在2周~2个月内接受治疗的患者,34例。慢性期组(Ⅲ组):症状出现2个月后接受治疗者,18例。观察各组症状改善、骨折复位及并发症发生情况。[结果]术后各组患者的疼痛症状都得到迅速而有效的缓解。3组术后VAS评分均较术前明显降低(P<0.05),组间比较差异无显著性(P>0.05)。Ⅰ、Ⅱ组椎体平均高度及局部Cobb角均有显著恢复(P<0.05),而Ⅲ组手术前后差异无统计学意义(P>0.05)。Ⅰ、Ⅲ组的近远期并发症发生率分别为33.3%和38.9%,Ⅱ组并发症发生率为11.8%,组间比较差异有显著性(P<0.05)。[结论]经皮椎体后凸成形术能有效缓解任何时期椎体压缩骨折所致的疼痛,尤其对处于早期修复期的骨折患者,可在最小的并发症风险下获得最佳的临床疗效。
关键词(KeyWords): 经皮椎体后凸成形术;不同时期;骨质疏松性压缩骨折;临床疗效
基金项目(Foundation):
作者(Author): 刘法敬;申勇;张英泽;丁文元;杨大龙;徐佳欣;任虎;
Email:
DOI:
参考文献(References):
- [1]Genant HK,Cooper C,Poor G,et al.Interim report and recommenda-tion of the World Health Organization Task Force for Osteoporosis[J].Osteoporos Int,1999,4:259-264.
- [2]Phillips FM,Todd Wetzel F,Lieberman I,et al.An in vivo comparisonof the potential for extravertebral cement leak after vertebroplasty andkyphoplasty[J].Spine,2002,27:2173-2178.
- [3]Phillips FM.Minimally invasive treatments of osteoporotic vertebralcompression fractures[J].Spine,2003,28:45-53.
- [4]Melton LR.Perspective:howmany women have osteoporosis now[J].JBone Miner Res,1995,10:175-177.
- [5]Phillips FM,Ho E,Campbell HM,et al.Early radiographic and clini-cal results of balloon kyphoplasty for the treatment of osteoporotic ver-tebral compression fractures[J].Spine,2003,28:2260-2265.
- [6]倪文飞,池永龙,林焱,等.经皮椎体强化术并发骨水泥渗漏的类型及其临床意义[J].中华外科杂志,2006,4:231-234.
- [7]Belkof SM,Mathis JM,Erbe EM,et a1.Biomechanical evalution of anew bone cement for use in vertebroplasty[J].Spine,2000,9:1061-1064.
- [8]Coumans JV,Reinhardt MK,Lieberman IH.Kyphoplasty for vertebralcompression fractures:1-year clinical outcomes from a prospectivestudy[J].Neurosurgery,2003,1:44-50.
- [9]胡永胜,马原,田慧中,等.经皮椎体成形术的临床应用[J].中国矫形外科杂志,2007,18:1392-1394.
- [10]Hadjipavlou GA,Tzermiadianos NM,Katonis GP,et al.Percutaneous-vertebroplasty and balloon kyphoplasty for the treatment of osteoporoticvertebral compression fractures and osteolytic tumours[J].J Bone andJoint Surg Br,2005,12:1595-1604.
- [11]Erkan S,Ozalp TR,Yercan HS,et al.Does timing matter in performingkyphoplasty?Acute versus chronic compression fractures[J].Acta Or-thop Belg,2009,3:396-404.
- [12]任虎,申勇,张英泽,等.经皮椎体后凸成形术对新鲜与陈旧性骨质疏松性椎体压缩骨折的疗效对比分析[J].中国矫形外科杂志,2009,18:1361-1364.
- [13]Pflugmacher R,Schroeder RJ,Klostermann CK.Incidence of adjacentvertebral fractures in patients treated with balloon kyphoplasty:twoyears'prospective follow-up[J].Acta Radiol,2006,8:830-840.
- [14]Weber CH,Kr tz M,Hoffmann RT,et al.CT-guided vertebroplasty andkyphoplasty:comparing technical success rate and complications in101 cases[J].Rofo,2006,6:610-617.
- [15]Fribourg D,Tang C,Sra P,et al.Incidence of subsequent vertebralfracture after kyphoplasty[J].Spine,2004,20:2270-2277.