梁建平;刘兴炎;葛宝丰;陈克明;熊发明;李荣刚;

• 1:兰州军区兰州总医院创伤外科

摘要(Abstract)：

[目的]证实磷酸钙骨水泥复合少量自体颗粒骨修复骨缺损的效果,为临床使用提供依据。[方法]手术造成日本大耳白兔双侧桡骨中段15 mm缺损,一侧植入磷酸钙骨水泥与自体颗粒骨以3∶1复合的材料,做为实验组;另一侧植入单纯的磷酸钙骨水泥,做为对照组。在不同的时间点行X线、骨密度、最大扭矩检测,分析实验组及对照组的成骨性能和材料降解程度。[结果]X线检查发现:实验组材料明显促进成骨,8周时材料周围有明显的骨痂,16周时缺损完全修复、材料完全降解,优于对照组;8、16周时,实验组单位面积的骨矿盐含量均高于对照组,统计学检测,P<0.01;16周时实验组和对照组的最大扭矩分别为:(0.843±0.016)mN、(0.540±0.029)mN,统计学检验P<0.01。[结论]磷酸钙骨水泥与自体颗粒骨以3∶1复合后明显促进了缺损修复和材料降解。

关键词(KeyWords)： 磷酸钙骨水泥;微小颗粒骨;骨缺损;兔

Abstract:

Keywords:

基金项目(Foundation): 全军“十一五”医药卫生科研基金资助项目(编号:06MA090);; 甘肃省自然科学基金资助项目(编号:0710RJZA068)

作者(Author): 梁建平;刘兴炎;葛宝丰;陈克明;熊发明;李荣刚;

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参考文献(References)：

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