刘仁德;蔡广荣;张恒;罗斯敏;

• 1:东莞市麻涌医院
• 2:韶关市第一人民医院
• 3:暨南大学第一附属医院

摘要(Abstract)：

[目的]探讨低血栓风险人群术前D-二聚体升高对膝关节置换术后下肢深静脉血栓(DVT)形成的影响。[方法]采用病例对照研究方式,系统回顾本院2016年9月～2018年1月行单侧全膝关节置换术的198例患者资料,其中术后发生DVT的患者共77例列入血栓组,未发生DVT的患者121例列入对照组,比较两组年龄、BMI、血压、和术前D-二聚体升高、血脂异常、糖尿病史比率,筛选与术后血栓形成相关的危险因素,并进行多因素逻辑回归分析。[结果]血栓组的年龄(65.61±7.92)岁均大于对照组(62.53±7.75)岁,差异有统计学意义(P<0.05);血栓组BMI (28.61±3.01) kg/m2大于对照组(27.24±3.04) kg/m2,差异有统计学意义(P<0.05)。血栓组术前D-二聚体升高比率显著大于对照组(OR=5.337, 95%CI 2.388～11.923, P<0.05)。逻辑回归分析表明术前D-二聚体升高(OR=5.162, 95%CI 2.321～11.467)和BMI (OR=1.639, 95%CI 1.051～2.582)是术后血栓形成的独立的危险因素。[结论]术前D-二聚体升高患者术后发生血栓的风险是D-二聚体正常患者的5.162倍;患者BMI (体重正常BMI<24,超重24≤BMI<28,肥胖BMI≥28)每跨越一个等级,术后血栓风险增加1.639倍。

关键词(KeyWords)： 全膝关节置换术;深静脉血栓形成;D-二聚体

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 刘仁德;蔡广荣;张恒;罗斯敏;

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