侯晓;李纯璞;陈元振;倪梅;郭冬梅;张开刚;

• 1:山东省泰安市中心医院

摘要(Abstract)：

骨肉瘤是最常见的骨恶性肿瘤之一,很多报道均已证明Notch信号通路与肿瘤细胞的增殖、分化及转移等有着内在的联系。最新研究表明Notch通路与骨肉瘤的增殖、分化及耐药性等也有一定的相关性。了解Notch通路与骨肉瘤及其血管形成的关系可为临床预防及诊治骨肉瘤提供可靠的理论依据,有利于拓展预防和治疗骨肉瘤的新途径。

关键词(KeyWords)： Notch信号通路;骨肉瘤;分子机制

Abstract:

Keywords:

基金项目(Foundation): 山东省自然科学基金(项目编号:ZR2012HL38);; 山东省优秀中青年科学家科研奖励基金(项目编号:BS2013SF030)

作者(Author): 侯晓;李纯璞;陈元振;倪梅;郭冬梅;张开刚;

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