刘林;杨治;姚建锋;许鹏;张育民;许珂;张银刚;

• 1:西安交通大学医学院附属红会医院关节科
• 2:西安交通大学医学院第一附属医院骨科

摘要(Abstract)：

<正>负压封闭引流技术(vacaum assisted closure,VAC)自上世纪50年代被提出,经过改进于80年代末开始用于慢性复杂性创面的治疗,1997年Morykwas和Argenta首先描述了VAC在动物实验和临床软组织损伤中的使用效果[1-2]。VAC通过其对软组织的机械性和生物学效应,可以刺激血管增生、改善血液循

关键词(KeyWords)： 负压封闭引流;创面修复;临床应用

Abstract:

Keywords:

基金项目(Foundation): 国家自然基金资助项目(编号:30973063);; 陕西省卫生厅科研基金项目(编号:2010D23);; 西安市卫生局科技立项项目(编号:J2010B31)

作者(Author): 刘林;杨治;姚建锋;许鹏;张育民;许珂;张银刚;

Email:

DOI:

参考文献(References)：

• [1]Morykwas MJ,Argenta LC,Shelton-Brown EI,et al.Vacuum-assisted closure:a new method for wound control and treatment:animal studies and basic foundation[J].Ann Plast Surg,1997,6:553-562.
• [2]Argenta LC,Morykwas MJ.Vacuum-assisted closure:a new method for wound control and treatment:clinical experience[J].Ann Plast Surg,1997,6:563-576.
• [3]Streubel PN,Stinner DJ,Obremskey WT.Use of negative-pressure wound therapy in orthopaedic trauma[J].J Am Acad Orthop Surg,2012,9:564-574.
• [4]Stannard JP,Gabriel A,Lehner B.Use of negative pressure wound therapy over clean,closed surgical incisions[J].Int Wound J,2012,1:32-39.
• [5]Orgill DP,Manders EK,Sumpio BE,et al.The mechanisms of action of vacuum assisted closure:more to learn[J].Surgery,2009,1:40-51.
• [6]Collinge C,Reddix R.The incidence of wound complications related to negative pressure wound therapy power outage and interruption of treatment in orthopaedic trauma patients[J].J Orthop Trauma,2011,2:96-100.
• [7]Hou Z,Irgit K,Strohecker KA,et al.Delayed flap reconstruction with vacuum-assisted closure management of the open IIIB tibial fracture[J].J Trauma,2011,6:1705-1708.
• [8]黄雄飞,余伟宏.负压封闭引流治疗Ⅲ度开放性骨折的创面[J].中国矫形外科杂志,2010,7:606-607.
• [9]Greer S,Kasabian A,Thorne C,et al.The use of a subatmospheric pressure dressing to salvage a Gustilo grade IIIB open tibial fracture with concomitant osteomyelitis to avert a free flap[J].Ann Plast Surg,1998,6:687.
• [10]Fleischmann W,Lang E,Kinzl L.Vacuum assisted wound closure after dermatofasciotomy of the lower extremity[J].Unfallchirurg,1996,4:283-287.
• [11]孙士锦,姚元章,麻晓林,等.负压封闭技术治疗骨筋膜室综合征[J].中国修复重建外科杂志,2004,2:163.
• [12]Venturi ML,Attinger CE,Mesbahi AN,et al.Mechanisms and clinical applications of the vacuum-assisted closure(VAC)device[J].Am J Clin Dermatol,2005,3:185-194.
• [13]Lejay A,Creton O,Thaveau F,et al.Current clinical applications of vacuum-assisted closure(VAC)in vascular surgery[J].J Mal Vasc,2008,4-5:196-201.
• [14]Banwell PE,Evison D,Whitworth IM.Vacuurn therapy in degloving injuries of the foot:technical refinements[J].Br J Plast Surg,2002,3:264-266.
• [15]Meara JG,Guo L,Smith JD,et al.Vacuum-assisted closure in the treatment of degloving injuries[J].Ann Plast Surg,1999,6:589-594.
• [16]Andrews BT,Smith RB,Chang KE,et al.Management of the radial forearm free flap donor site with the vacuum-assisted closure(VAC)system[J].Laryngoscope,2006,10:1918-1922.
• [17]Weinand C.The vacuum-assisted closure(VAC)device for hastened attachment of a superficial inferior-epigastric flap to third-degree burns on hand and fingers[J].J Burn Care Res,2009,2:362-365.
• [18]余黎,余国荣,陶圣祥,等.负压封闭引流在毁损性断肢再植中的应用[J].中华创伤骨折杂志,2008,1:44-48.
• [19]梅海龙,陶圣祥,孔抗美,等.负压闭式引流在断肢再植中的临床应用[J].汕头大学医学院学报,2006,3:172-174.
• [20]Lam WL,Garrido A,Stanley PR.Use of topical negative pressure in the treatment of chronic osteomyelitis[J].J Bone Joint Surg Am,2005,3:622-624.
• [21]Timmers MS,Graafland N,Bernards AT,et al.Negative pressure wound treatment with polyvinyl alcohol foam and polyhexanide antiseptic solution instillation in posttraumatic osteomyelitis[J].Wound Rep Reg,2009,2:278-286.
• [22]Horn PL,Ruth B,Kean JR.Use of wound V.A.C.therapy in pediatric patients with infected spinal wounds:a retrospective review[J].Orthop Nurs,2007,5:317-322.
• [23]Genecov DG,Schneider AM,Morykwas MJ,et al.A controlled subatmospheric pressure dressing increases the rate of skin graft donor site reepithelialization[J].Ann Plast Surg,1998,3:219-225.
• [24]Potter MJ,Banwell P,Baldwin C,et al.In vitro optimisation of topical negative pressure regimens for angiogenesis into synthetic dermal replacements[J].Burns,2008,2:164-174.
• [25]Labanaris AP,Polykandriotis E,Horch RE.The effect of vacuum-assisted closure on lymph vessels in chronic wounds[J].J Plast Reconstr Aesthet Surg,2009,8:1068-1075.
• [26]柏士平,潘拥军,宗艳霞.负压封闭引流结合臀大肌肌皮瓣在骶尾部褥疮修复中的应用[J].中国矫形外科杂志,2012,1:27-29.
• [27]De Lange MY,Schasfoort RA,Obdeijn MC,et al.Vacuum-assisted closure:indications and clinical experience[J].Eur J Plast Surg,2000,4:178-182.
• [28]Gabriel A,Shores J,Heinrich C,et al.Negative pressure wound therapy with instillation:a pilot study describing a new method for treating infected wounds[J].Int Wound J,2008,3:399-413.
• [29]Chariker ME,Gerstle TL,Morrison CS,et al.An algorithmic approach to the use of gauze-based negative-pressure wound therapy as a bridge to closure in pediatric extremity trauma[J].Plast Reconstr Surg,2009,5:1510-1520.
• [30]Canavese F,Krajbich JI,Kuang AA.Application of the vacuum-assisted closure in pediatric patients with orthopedic sequelae of meningococcemia:report of a case successfully treated[J].J Pediatr Orthop B,2009,9:1097-1101.