糖皮质激素在骨关节炎中的研究进展Research progress on glucocorticoids used in osteoarthritis
胡元一;张启栋;
摘要(Abstract):
骨关节炎是一种关节退行性疾病,其特征是关节软骨和软骨下骨逐渐丧失,并伴有不同程度的滑膜炎症。糖皮质激素具有强大的抗炎作用,能对抗各种原因如物理、化学、生物、免疫等引起的炎症。因其抗炎止痛效果好、作用迅速,临床常常应用合成糖皮质激素治疗骨关节炎,尤其是在关节腔注射治疗中。本综述将探讨糖皮质激素在骨关节炎中的研究进展,以期为优化骨关节炎疗法提供参考。
关键词(KeyWords): 骨关节炎;粮皮质激素;机制
基金项目(Foundation): 国家自然科学基金(编号:81703896)
作者(Author): 胡元一;张启栋;
Email:
DOI:
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