徐广春;程立明;郭万首;

• 1:卫生部中日友好医院

摘要(Abstract)：

软骨延迟增强磁共振成像(delayed gadolinium-enhanced MRI of cartilage,dGEMRIC)是一种分子成像技术,借助增强剂钆喷酸葡胺(Gd-DTPA2)的存在,利用计算机图像处理软件,将获得的T1值绘制成T1图像,用以评价关节软骨中糖胺聚糖(glycosaminoglycan,GAG)的分布状况[1]。Bashir等于上世纪90年代经过实验证实,静脉注射Gd-DTPA2经过一段时间后,Gd-DTPA2可分布至关节软骨,通过MRI成像所测T1值与软骨中GAG含量呈正相关,从而为dGEMRIC技术奠定了初步的理论基础[2-3]。近年来dGEMRIC逐步开始应用于检测早期骨性关节炎软骨退变[4]、股骨头坏死[5]及髋关节发育不良[6]所造成的关节软骨损害、自体软骨细胞移植后疗效评估[7]及关节外伤软骨改变[8]等。本文主要对dGEMRIC技术主要原理、临床应用进展等方面进行综述。

关键词(KeyWords)： 延迟增强磁共振;软骨;关节疾病

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 徐广春;程立明;郭万首;

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参考文献(References)：

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