高正玉;王英振;徐红梅;王昌耀;吴继霞;

• 1:青岛大学医学院附属医院关节科
• 2:青岛大学医学院附属医院麻醉科
• 3:山东省昌乐县妇幼保健站

摘要(Abstract)：

[目的]研究全膝关节置换(total knee arthroplasty,TKA)术中关节周围注射罗哌卡因、酮洛酸氨丁三醇、肾上腺素混合药物,联合术后关节腔内注射罗哌卡因、酮洛酸氨丁三醇对TKA的镇痛效果、术后康复的影响及副作用。[方法]选择在本院行单侧TKA的50例患者随机分为两组,研究组术中将罗哌卡因、酮洛酸氨丁三醇、肾上腺素的混合液注射在膝关节周围,术后48h拔除引流管后,关节腔内注入罗哌卡因、酮洛酸氨丁三醇。对照组术中、术后均给予相同剂量的生理盐水作为对照。记录视觉模拟评分(VAS)、Rameasay镇静评分,CPM膝关节活动度及副作用,应用统计软件SPSS13.0进行统计学分析。[结果]研究组术后6、12、24h,第3、4d的VAS评分均低于对照组,(t=3.49～2.34,P<0.05),第2d时VAS评分无差别(t=1.99,P>0.05),CPM膝关节活动度在术后2～6d高于对照组(t=3.030～2.112,P<0.05),而在第7d以后活动度无差别(t=1.997～2.020,P>0.05)。两组副作用无差别(x2值1.657a,P>0.05)。[结论]TKA术中关节周围注药联合术后关节腔内注药可在术后早期减轻疼痛、改善关节活动度、促进康复,且不会增加副作用。

关键词(KeyWords)： 人工假体;全膝关节;局部注药;镇痛

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 高正玉;王英振;徐红梅;王昌耀;吴继霞;

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参考文献(References)：

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