苑伟;段王平;陈崇伟;李鹏翠;卫小春;

• 1:山西医科大学第二医院骨科
• 2:骨与软组织损伤修复山西省重点实验室

摘要(Abstract)：

[目的]通过Meta分析评价两种非骨水泥假体:生物型组配式假体与涂层长柄假体,在髋关节翻修术治疗骨缺损时临床疗效的差异。[方法]文献检索PubMed、Ovid、CochraneLibrary、ScienceDirect、SpringerLink数据库,根据纳入和排除标准筛选文献,收集组配式假体与涂层长柄假体在髋关节翻修术中应用的高质量随机对照研究,提取相关数据,采用Review Manager 5.0软件进行Meta分析。[结果]共纳入8篇随机对照研究(Jadad评分3~5分)。Meta分析结果显示,组配式假体与涂层长柄假体在髋关节翻修术后并发症的发生率无统计学差异RR=1.12,95%CI(0.96,1.32),P=0.15;组配式假体在髋关节翻修术后假体塌陷的发生率低于涂层长柄假体RR=0.28,95%CI(0.08,0.95),P=0.04;术后疼痛的发生率也低于涂层长柄假体RR=0.45,95%CI(0.22,0.94),P=0.03;两种假体在髋关节翻修术后假体无菌性松动的发生率无统计学差异RR=1.39,95%CI(0.21,9.39),P=0.74。[结论]髋关节翻修术应用组配式假体相对于涂层长柄假体可以减少术后疼痛和假体塌陷的发生率。

关键词(KeyWords)： 非骨水泥;组配式假体;涂层假体;髋关节翻修;Meta分析

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金资助项目(编号:31271033);; 教育部2012年高等学校博士学科点专项科研基金联合资助课题(编号:20121417120004)

作者(Author): 苑伟;段王平;陈崇伟;李鹏翠;卫小春;

Email:

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