唐晓杰;李成立;宋钦勇;陈树军;于冰;谭江威;

• 1:滨州医学院烟台附属医院

摘要(Abstract)：

[目的]评价经皮椎弓根固定联合通道下病灶清除载药硫酸钙颗粒椎间隙内植入治疗脊柱感染的疗效。[方法]回顾性分析2015年7月～2018年12月在本科行经皮椎弓根固定联合通道下病灶清除载药硫酸钙颗粒椎间隙内植入治疗脊柱感染的18例患者的临床资料。记录分析患者的手术时间、术中失血量、住院时间、VAS和ODI评分;以及血沉、CRP、Cobb角。[结果]本组的18例患者均顺利完成手术,手术过程中无神经损伤、脑脊液漏等并发症。术中病理及脓液或坏死组织培养结果:7例为金葡菌感染,1例为大肠埃希菌感染,2例结核杆菌感染,8例为阴性。手术切口均一期愈合。术后随访时间8～26个月,随访过程中无感染复发。末次随访时患者VAS、ODI评分、血沉及CRP均优于术前,差异具有统计学意义(P<0.05);末次随访与术前相比,Cobb角无变化(P>0.05)。[结论]脊柱感染患者,通道下病灶清除、硫酸钙抗生素骨粒植入、经皮固定手术是一种比较理想的治疗方法,维持稳定同时保持局部有效抗生素浓度,利于控制感染。

关键词(KeyWords)： 脊柱感染;经皮椎弓根螺钉内固定;通道;病灶清除;载抗生素硫酸钙

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金项目(编号：81470054);; 滨州医学院科研计划启动基金项目(编号：BY2018KJ37)

作者(Author): 唐晓杰;李成立;宋钦勇;陈树军;于冰;谭江威;

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DOI:

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