李博;胡如印;孙立;田家亮;田晓滨;

• 1:贵州省人民医院骨科

摘要(Abstract)：

[目的]探讨膝骨性关节炎(osteoarthritis,OA)膝关节液内微量元素的浓度与Outerbridge分级标准的关系。[方法]选择2012年1月~2014年1月本科确诊的膝关节OA患者160例,根据骨性关节炎关节镜下Outerbridge分级分4组,以40例健康体检者为对照,抽取各组膝关节液,检查关节液中铜、钙、镁、锌、铁元素的浓度。[结果]对照组与膝关节OA组关节液的铜、钙、镁、锌和铁浓度均有显著差异(P<0.01)。不同Outerbridge的膝关节OA组内关节液的铜、钙、镁、锌和铁浓度均有显著差异(P<0.01)。与Outerbridge分级相关的因素有关节液的钙、锌、铁和铜,其中铁为负相关(P<0.05或P<0.01),与镁无相关性。[结论]膝关节液中钙、锌、铁和铜的浓度变化可作为膝关节OA的诊断指标,且钙、锌、铁和铜与Outerbridge分级标准有相关性,可用作提示膝关节OA病变严重程度的指标。

关键词(KeyWords)： 微量元素;膝骨性关节炎;Outerbridge分级

Abstract:

Keywords:

基金项目(Foundation): 贵州省科技合作计划项目(编号:黔科合LH字[2015]7121号)

作者(Author): 李博;胡如印;孙立;田家亮;田晓滨;

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DOI:

参考文献(References)：

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