转化生长因子-β在骨髓间充质干细胞向软骨细胞定向分化过程中的作用
常献;陈斌;李长青;
摘要(Abstract):
<正>生长因子是细胞之间进行信息传递及调节细胞生长分化的一系列多肽,它能调控细胞的增殖、分化、迁移和基因表达。目前已经应用于软骨组织工程的生长因子种类繁多,主要有转化生长因子家族、骨形态发生蛋白家族、成纤维细胞生长因子家族等。从骨髓间充质干细胞到软骨细胞这条定向的分化通路中,这些生长因子发挥着不同的促进作用并有协同性。转化
关键词(KeyWords): 骨髓间充质干细胞;细胞分化;软骨化;转化生长因子;信号通路
基金项目(Foundation):
作者(Author): 常献;陈斌;李长青;
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DOI:
参考文献(References):
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