李宏达;夏群;刘佳男;魏冬;胥鸿达;

• 1:天津医科大学研究生院
• 2:天津市天津医院
• 3:天津中医药大学研究生院

摘要(Abstract)：

[目的]比较颈椎间盘置换和前路融合两种不同手术方式对相邻节段在体运动影响。[方法]计算机检索Cochrane library、Pubmed、Ovid、ELSEVIER Science Direct、Springerlink、中国期刊全文数据库、万方数据库、中国生物医学文献数据库(时间截至2014年10月),手工检索相关杂志,纳入有关人工颈椎间盘置换和前路融合术后相邻节段在体运动学研究的文献,利用Rev Man5.3(下载于Cochrane Library)进行Meta分析,选取手术部位相邻上下节段矢状面运动范围、C2~7整体矢状面运动范围等指标进行比较分析。[结果]经过筛选,16篇文献符合纳入标准,共1 666例。Meta分析结果显示:前路融合术后手术部位上方相邻节段矢状面运动范围增大:随机对照组[MD=-1.34,95%CI(-2.39,-0.30),P=0.01],非随机对照组[MD=-1.38,95%CI(-1.61,-1.14),P<0.00001];下方相邻节段矢状面运动范围也增大:随机对照组[MD=-1.23,95%CI(-1.63,-0.82),P<0.000 01],非随机对照组[MD=-1.85,95%CI(-2.82,-0.89),P=0.000 2];颈椎整体矢状面运动范围随机对照组示两种术式无差异[MD=1.70,95%CI(-3.29,6.69),P=0.50],而非随机对照组示间盘置换术后颈椎整体运动范围比前路融合组大[MD=8.31,95%CI(3.63,13.00),P=0.000 5]。[结论]颈椎前路融合术后相邻节段的活动范围比椎间盘置换增大,从一个侧面可能解释颈椎融合后相邻节段疾病发生率比人工颈椎间盘置换高的临床现象。

关键词(KeyWords)： 人工颈椎间盘置换;颈椎前路融合;相邻节段;在体运动;Meta分析

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 李宏达;夏群;刘佳男;魏冬;胥鸿达;

Email:

DOI:

参考文献(References)：

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