姜楠;覃承诃;余斌;

• 1:南方医科大学南方医院创伤骨科

摘要(Abstract)：

[目的]总结骨折内固定术后感染抗生素治疗的新进展。[方法]查阅近年关于骨折内固定术后感染抗生素治疗的相关文献,进行综述分析。[结果]系统抗生素的选择应参照细菌培养结果,抗生素用药时间一般不超过4~6周,口服与静脉疗效相似,但口服用药并发症发生率更低且花费更少;达托霉素在治疗骨感染中的疗效已引起关注;怀疑生物膜细菌感染时,应联合应用利福平或氟喹诺酮类抗生素;局部应用抗生素载体以硫酸钙为典型代表,其可完全降解,生物相溶性好,有良好的骨传导及药物缓释功能。[结论]合理的系统联合局部应用抗生素能有效降低内固定术后感染的复发率,提高患者生活质量。

关键词(KeyWords)： 内固定相关感染;骨髓炎;硫酸钙;抗生素治疗

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金(编号:31440043)

作者(Author): 姜楠;覃承诃;余斌;

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参考文献(References)：

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