人工关节松动的药物和基因治疗进展
陶崑;张先龙;沈灏;王琦;邵俊杰;彭晓春;
摘要(Abstract):
关键词(KeyWords):
基金项目(Foundation):
作者(Author): 陶崑;张先龙;沈灏;王琦;邵俊杰;彭晓春;
Email:
DOI:
参考文献(References):
- [1]张超,汤亭亭,戴尅戎.人工关节无菌性松动药物治疗进展[J].中国矫形外科杂志,2007,11:836-839.
- [2]Wooley PH,Schwarz EM.Aseptic loosening[J].Gene Ther,2004,4:402-407.
- [3]Shanhhag AS.Use of bisphospbonates to improve the durability of to-tal joint replacements[J].J Am Acad Orthop Surg,2006,4:215-225.
- [4]Wise LM,Waldman SD,Kasra M,et al.Effect of zoledrnnate on bone quality in the treatment of aseptic loosening of hip arthroplasty in the dog[J].Calcif Tissue Int,2005,6:367-375.
- [5]Bhandari M,Bajammal S,Guyatt GH,et al.Effect of bisphospbonates on periprosthetic bone mineral density after total joint arthroplasty.A meta-analysis[J].J Bone Joint Surg(Am),2005,2:293-301.
- [6]Shanbhag AS.Use of bisphosphonates to improve the durability of to-tal joint replacements[J].J Am Acad Orthop Surg,2006,4:215-225.
- [7]Munns CF,Rauch F,Mier RJ,et al.Respiratory distress with pamidr-onate treatment in infants with severe osteogenesis impeffecta[J].Bone,2004,35:231-234.
- [8]Woo SB,Hellstein JW,Kalmar JR.Systemic review:bisphosphonates and osteonecrosis of the jaws[J].Ann Intern Med,2006,144:753-761.
- [9]Cornish J,Callon KE,Bava U,et al.Effects of calcitonin,amylin,and calcitonin gene-related peptide on osteoclast development[J].Bone,2001,29:162-168.
- [10]范卫民,马益民,王青.帕米磷酸钠和降钙素对人工关节磨损微粒引起单核细胞分泌溶骨性因子的影响[J].中华实验外科杂志,2003,20:659-660.
- [11]Peichl P,Griesmacher A,Kumpan W,et al.Clinical outcome of salm-on calcitonin nasal spray treatment in postmenopausal women after to-tal hip arthroplasty[J].Gerontology,2005,4:242-252.
- [12]Ren WP,Li XY,Chen BD,et al.Erythromycin inhibits wear debris-induced osteoclastogenesis by modulation of murine macrophage NFkB activity[J].J Orthop Res,2004,22:21-29.
- [13]Desaki M,Okazaki H,Sunazuka T,et al.Molecular mechanisms of anti-inflammatory action of erythromycin in human bronchial epitheli-al cells:possible role in the signaling pathway that regulates nuclear factor-{kappa}b activation[J].Antimicrob Agents Chemother,2004,48:1581-1585.
- [14]Ren W,Wu B,Peng X,et al.Erythromycin inhibits wear debris-in-duced inflammatory osteolysis in a murine model[J].J Orthop Res,2006,2:280-290.
- [15]Jacobs JJ,Roebuck KA,Archibeck M,et al.Osteolysis:basic science[J].Clin Orthop Relat Res,2001,393:71-77.
- [16]Ong SM,Taylor GJ.Doxycycline inhibits bone resorption by human interface membrane cells from aseptically loose hip replacements[J].J Bone Joint Surg(Br),2003,3:456-461.
- [17]Staal A,Frith JC,French MH,et al.The ability of statins to inhibit bone resorption is directly related to their inhibitory effect on HMG-CoA reductase activity[J].J Bone Miner Res,2003,1:88-96.
- [18]von Knoch F,Heckelei A,Wedemeyer C,et al.The effect of simvasta-tin on polyethylene particle-induced osteolysis[J].Biomaterials,2005,17:3549-3555.
- [19]Persson PE,Nilsson OS,Bevggren AM.Do non-steroidal anti-inflam-matory drugs cause endoprosthetic loosening?A10-year follow-up of a randomized trial on ibuprofen for prevention of heterotopic ossifica-tion after hip arthroplasty[J].Acta Orthop,2005,6:735-740.
- [20]Schwarz EM,Benz EB,Lu AP,et al.Quantitative small-animal surro-gate to evaluate drug efficacy in preventing wear debris-induced oste-olysis[J].J Orthop Res,2000,6:849-855.
- [21]Pollice PF,Rosier RN,Looney PO,et al.Oral pentoxifylline inhibits release of tumor necrosis factor-alpha from human peripheral blood monocytes:a potential treatment for aseptic loosening of total joint components[J].J Bone Joint Surg(Am),2001,7:1057-1061.
- [22]Bathon JM,Martin RW,Fleischmann RM,et al.A comparison of et-anercept and methotrexate in patients with early rheumatoid arthritis[J].N Engl J Med,2000,343:1586-1593.
- [23]Schwarz EM,Campbell D,Totterman S,et al.Use of volumetric com-puterized tomography as a primary outcome measure to evaluate drug efficacy in the prevention of peri-prosthetic osteolysis:a l-year clinical pilot of etanercept vs.placebo[J].J Orthop Res,2003,6:1049-1055.
- [24]Cohen S,McClung M,Lewiecki E,et al.AMG162Administered ev-ery6months causes rapid and sustained decreases in bone turnover in postmenopausal women with low bone mineral density(BMD)[J].Arthritis Rheum,2005,1:438.
- [25]Looney PO,Schwarz EM,Boyd A,et al.Periprosthetic osteolysis:an immunologist's update[J].Curt Opin Rheumatol,2006,1:80-87.
- [26]Ren W,Zhang R,Markel DC,et al.Blockade of vascular endothelial growth factor activity suppresses wear debris-induced inflammatory os-teolysis[J].J Rhemnatol,2007,1:27-35.
- [27]Sud S.Effects of cytokine gene therapy on particulateinduced inflam-mation in the murine air pouch[J].Inflammation,2001,25:361-372.
- [28]Yang SY,Wu B,Mayton L,et al.Protective effects of IL-I Ra or vlL-10gene transfer on a murine model of wear debris-induced osteol-ysis[J].Gene Ther,2004,5:483-491.
- [29]Childs LM,Goater JJ,O'Keefe PO,et al.Effect of antitumor necrosis factor-alpha gene therapy on wear debrisinduced osteolysis[J].J Bone Joint Surg(Am),2001,83:1789-1797.
- [30]Trindade MC,Lind M,Nakashima Y,et al.Interleukin-10inhibits polymethylmethacrylate particle induced imerleukin-6and tumor nec-rosis factor-alpha release by human monocyte/macrophages in vitro[J].Biomaterials,2001,22:2067-2073.
- [31]Kim KN,Watanabe S,Ma Y,et al.Viral IL-10and soluble TNF re-ceptor act synergistically to inhibit collagen-induced arthritis following adenovirus-mediated gene transfer[J].J Immunol,2000,164:1576-1581.
- [32]Carmody EE.Viral interleukin-10gene inhibition of inflammation,os-teoclastogenesis,and bone resorption in response to titanium particles[J].Arthritis Rheum,2002,46:1298-1308.
- [33]Goater JJ.Efficacy of ex vivo OPG gene therapy in preventing wear debris induced osteolysis[J].J Orthop Res,2002,20:169-173.
- [34]Ulrich-Vinther M.Recombinant adeno-associated virus mediated os-teoprotegerin gene therapy inhibits wear debris induced osteolysis[J].J Bone Joint Surg(Am),2002,84:1405-1412.