覃宇宙;蔡贤华;刘曦明;谭宗奎;钟炎军;

• 1:解放军武汉总医院骨科

摘要(Abstract)：

[目的]观察改良创伤严重度评分法(RISS)结合药物预防骨创伤并发脂肪栓塞(FES)的效果。[方法]采用前瞻性研究2016年3月～2017年10月收治的骨创伤患者1305例,根据是否合并胸、腹、颅脑等其他部位的多发损伤和RISS分值,将患者分为四组:A组104例为单纯四肢长管状骨骨折,RISS分值<11分;B组256例为单纯四肢长管状骨骨折,RISS分值≥11分;C组358例为四肢长管状骨骨折同时合并有多发损伤,RISS分值<18分;D组587例为四肢长管状骨骨折同时合并有多发损伤,且RISS分值≥18分。其中A、C两组不给予药物预防措施,B、D两组给予低分子右旋糖酐加地塞米松药物预防,观察FES的预防效果。[结果] 1 305例骨创伤患者中,发生临床FES 3例,男女比例为2:1,平均年龄为(38.32±13.22)岁。A组和C组均无FES发生;B组发生1例FES,RISS分值为13分;D组发生2例FES,其RISS分值分别为21分和25分。各组患者性别、年龄和入院时间差异无统计学意义(P>0.05),各组RISS值比较差异具有统计学意义(P<0.05)。[结论]应用RISS评分法对骨创伤易并发FES患者进行快速筛选并给予药物预防,有肋于降低FES的发病率。

关键词(KeyWords)： 骨创伤;创伤严重度改良评分法;脂肪栓塞综合征;预防

Abstract:

Keywords:

基金项目(Foundation): 湖北省卫生计生科研基金(编号:WJ2015MA013)

作者(Author): 覃宇宙;蔡贤华;刘曦明;谭宗奎;钟炎军;

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DOI:

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