许小多;于秀淳;黄伟敏;孔令南;

• 1:锦州医科大学济南军区总医院培养基地
• 2:济南军区总医院骨病科

摘要(Abstract)：

[目的]通过体外生物力学实验分析PEEK棒椎弓根螺钉内固定系统对相邻节段椎间盘内压力(Intradiscal pressure,IDP)的影响。[方法]取10具适当长度新鲜的羊脊柱标本(L_3~L_6),对每具标本依次行不同方式内固定处理,依据处理方式分为以下5个实验组:未处理组(Intact组)、钛棒单节段融合组(TS组)、PEEK棒单节段融合组(PS组)、PEEK棒双节段杂交组(PD组)和钛棒双节段融合组(TD组)。每个标本通过MTS多自由度脊柱运动模拟测试系统完成前屈、后伸、左/右侧弯、左/右扭转6个方向的完整动作。轴向压力为50 N,扭矩大小为:3 N.m。运用针孔式压力传感器测试每个方向运动状态下的椎间盘压力值。[结果]TS组及PS组的上位邻近节段IDP值高于Intact组(P<0.05);PS组上位相邻节段椎间盘压力值明显低于TS组(P<005);PD组过渡阶段椎间盘压力值明显低于TS组上位相邻节段椎间盘压力值(P<0.05);PD组上位相邻节段椎间盘压力值明显低于TD组(P<0.05)。[结论]与坚强固定相比,应用PEEK棒椎弓根螺钉内固定系统可显著降低相邻节段椎间盘内压力,这可能是降低相邻节段退变发生的理论基础。

关键词(KeyWords)： 相邻节段退变;PEEK棒椎弓根螺钉内固定系统;椎间盘内压力;生物力学

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 许小多;于秀淳;黄伟敏;孔令南;

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