余清文;赵东升;郑晓勇;刘道宏;

• 1:解放军第309医院创伤骨科

摘要(Abstract)：

[目的]系统评价Masquelet技术治疗创伤后骨缺损的治愈率及并发症的发生率。[方法]计算机检索Pubmed、EMbase、SCI、OVID循证数据库,收集Masquelet技术治疗骨折后骨缺损的研究,检索时间从建库至2018年4月。由2名研究者独立收集、筛选文献、提取资料,采用STATA12.0软件,依据效应指标为率的单臂研究荟萃分析方法进行分析。[结果]共纳入21个研究,包括594例患者。荟萃分析结果表明:融合所有研究报道的结果,Masquelet技术治疗骨折后骨缺损的治愈率为87.8%(CI 95%:84.9%～90.4%);术后再感染的发生率为9.2%(CI95%:5.3%～14%);术后骨不连的发生率为5.7%(CI 95%:2.8%～9.5%)。[结论]应用Masquelet技术治疗创伤后骨缺损有很高的治愈率,但仍然存在不容忽视的感染复发和骨不愈合的风险。

关键词(KeyWords)： Masquelet技术;膜诱导技术;骨缺损;骨不连

Abstract:

Keywords:

基金项目(Foundation): 全军医学科技青年培育计划拔尖项目(编号:17QNP036)

作者(Author): 余清文;赵东升;郑晓勇;刘道宏;

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DOI:

参考文献(References)：

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