高血压对全膝关节置换术围手术期出血的影响Effect of hypertension on perioperative bleeding in total knee arthroplasty
韩宁;姚建华;黄炎;李海鹏;孙维;王易彬;
摘要(Abstract):
[目的]研究高血压对全膝关节置换术围手术期出血的影响。[方法]回顾性分析2013年1月~2014年12月于本院关节外科接受全膝关节置换的患者,从中严格筛选符合本研究的病例126例,根据患者有无高血压病史及围手术期血压值分为高血压组和正常组,记录患者性别、年龄、身高、体重、围手术期血压、血红蛋白(Hb)、红细胞压积(Hct)、术后引流量、自体引流血回输量、术后输血量。运用Gross方程计算总出血量、隐性出血量。[结果]高血压组与正常组相比总出血量、隐性出血量差异有统计学意义(P=0.03,P=0.04),正常组男性与女性相比总出血量、隐性出血量及Hb下降差异有统计学意义(P=0.002,P=0.016,P=0.04),高血压组男性出血量与女性出血量差异无统计学意义(P=0.735)。[结论]高血压可明显增加全膝关节置换患者围手术期总出血量及隐性出血量。
关键词(KeyWords): 全膝关节置换术;高血压;出血
基金项目(Foundation):
作者(Author): 韩宁;姚建华;黄炎;李海鹏;孙维;王易彬;
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参考文献(References):
- [1]Dieppe P,Lim K,Lohmander S.Who should have knee joint replacement surgery for osteoarthritis[J].Int J Rheum Dis,2011,5(14):175-180.
- [2]Lotke PA,Faralli VJ,Orenstein EM,et al.Blood loss after total knee replacement.Effects of tourniquet release and continuous passive motion[J].J Bone Joint Surg Am,1991,73(7):1037-1040.
- [3]马丽娜,汤哲,赵晓玲,等.北京城乡老年人高血压现状调查[J].中华老年心脑血管病杂志,2010,12(2):127-129.
- [4]SkyttET,Haapamki V,Koivikko M,et al.Reliability of the hip-to-ankle radiograph in determining the knee and implant alignment after total knee arthroplasty[J].Acta Orthop Belg,2011,77(3):329-335.
- [5]Ma J,Huang Z,Shen B,et al.Blood management of staged bilateral total knee arthroplasty in a single hospitalization period[J].J Orthop Surg Res,2014,13(1):116.
- [6]Nadler SB,Hidalgo JH,Bloch T.Prediction of blood volume in normal human adults[J].Surgery,1962,51(2):224-232.
- [7]Ward CF,Meathe EA,Benumof JL,et al.A computer nomogram for blood loss replacement[J].Anaesthesiology,1980,53(3):126.
- [8]Gross JB.Estimating allowable blood loss:corrected for dilution[J].Anesthesiology,1983,58(3):277-280.
- [9]高玉镭,李佩佳,田敏,等.人工全膝关节置换术隐性失血的发生机制及影响因素分析[J].中国矫形外科杂志,2012,20(3):209-212.
- [10]Sliva CD,Callaghan JJ,Goetz DD,et al.Staggered bilateral total knee arthroplasty performed four to seven days apart during a single hospitalization[J].J Bone Joint Surg Am,2005,87(87):508-513.
- [11]Gohlke P,Lamberty V,Kuwer I,et al.Vascular remodeling in systemic hypertension[J].Am J Cardiol,1993,71(1):2-7.
- [12]Prasad N,Padmanabhan V,Mullaji A.Blood loss in total knee arthroplasty:an analysis of risk factors[J].Int Orthop,2007,31(1):39-44.
- [13]Russo RR,Dasa V,Duarte R,et al.Post-operative hypertension after total knee arthroplasty and the effects on transfusion rates[J].PLo S One,2012,7(12):e50967.
- [14]Sehat KR,Evans RL,Newman JH.Hidden blood loss following hip and knee arthroplasty.Correct management of blood loss should take hidden loss into account[J].J Bone Joint Surg Br,2004,86(4):561-565.
- [15]Feng P,Zhang H,Zhang BY,et al.Plasma thrombomo-dulin changes in acute cerebral infarction or hypertention patients:an observation for verification[J].Neural Regen Res,2008,3(1):71-74.
- [16]张志奇,刘进,何爱珊,等.术前血沉值对女性骨关节炎患者人工全膝关节置换术围手术期输血影响[J].中华关节外科杂志(电子版),2013,7(5):646-650.
- [17]Aglietti P,Baldini A,Vena LM,et al.Effect of tourniquet use on activation of coagulation in total knee replacement[J].Clin Orthop,2000,105(371):169-177.
- [18]Sudoh N,Toba K,Akishita M,et al.Estrogen prevents oxidative stress-induced endothelial cell apoptosis in rats[J].Circulation,2001,103(5):724-729.
- [19]Yang ZG,Chen WP,Wu LD.Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty:a meta-analysis[J].J Bone Joint Surg Am,2012,94(94):1153-1159.
- [20]Noticewala MS,Nyce JD,Wang W,et al.Predicting need for allogeneic transfusion after total knee arthroplasty[J].J Arthroplasty,2012,27(6):961-967.
- [21]Hersekli MA,Akpinar S,Ozkoc G,et al.The timing of tourniquet release and its influence on blood loss after total knee arthroplasty[J].Int Orthop,2004,28(3):138-141.
- [22]姚建华,孙天胜,李海鹏,等.人工全膝关节置换术后自体引流血回输的临床效果[J].中国输血杂志,2012,25(3):195-197.
- [23]刘宏滨,张阳,刘宁,等.止血带与全膝关节置换术肺脂肪栓塞风险的实验研究[J].中华关节外科杂志(电子版),2011,5(2):186-192.
- [24]朱莉丽,马波,贺玲,等.不同血压状况对脑梗塞发病及预后的影响[J].实用临床医药杂志,2007,3(1):32-33.