踝关节侵袭性及恶性骨肿瘤的外科治疗Surgical treatment of aggressive and malignant tumors of the ankle
杨京彦;李栋;马焕芝;张伟;孙成良;
摘要(Abstract):
[目的]探讨踝关节侵袭性和恶性肿瘤的外科治疗方式及治疗效果。[方法]回顾性研究2006年1月~2013年8月期间18例踝关节侵袭性和恶性肿瘤的患者。男10例,女8例;平均年龄31.7岁(8~60岁)。恶性肿瘤12例,侵袭性肿瘤6例。肿瘤类型以骨肉瘤最多(5例),其次为骨巨细胞瘤4例。10例肿瘤发生在胫骨远端,7例位于腓骨远端,1例位于距骨。12例患者行不同方式的保肢治疗,6例患者行截肢治疗。[结果]平均随访40.3个月(12~90个月)。总体复发率16.7%。12例恶性肿瘤患者中,6例保肢患者生存率(3年83.3%,5年27.8%)与6例截肢患者生存率(3年83.3%,5年41.7%)相比差异无统计学意义。12例保肢患者术后踝关节平均功能评分(MSTS评分)为82.9%,患者的情绪接受评分最高(平均4.5分)。[结论]通过广泛的肿瘤切除辅以放化疗,可达到良好的局部控制和长期生存。保肢术能达到较高的功能评分,并提高患者心理接受程度。
关键词(KeyWords): 踝关节;侵袭性肿瘤;恶性肿瘤;手术治疗
基金项目(Foundation):
作者(Author): 杨京彦;李栋;马焕芝;张伟;孙成良;
Email:
DOI:
参考文献(References):
- [1]Dahlin DC,Unni KK.Bone tumors,4th edition[M].Charles C Thomas,Springfield,Illinois,1986:149-173,218-226,307-315.
- [2]毛宾尧,王毳,李新春,等.踝足部肿瘤和瘤样病变的流行病学特点、临床和预后[J].中国矫形外科杂志,2014,22(17):1622-1624.
- [3]Enneking WF,Dunham W,Gebhardt MC,et al.A system for the functional evaluation of reconstructive procedures after surgical treatment of tumors of the musculoskeletal system[J].Clin Orthop,1993,286(286):241-246.
- [4]Talbert ML,Zagars GK,Sherman NA,et al.Conservative surgery and radiation therapy for soft-tissue sarcoma of the wrist,hand,ankle,and foot[J].Cancer,1990,66(12):2482-2491.
- [5]Ozdemir HM,Yildiz Y,Yilmaz C,et al.Tumors of the foot and ankle:analysis of 196 cases[J].J Foot Ankle Surg,1997,36(6):403-408.
- [6]Temple HT,Worman DS,Mnaymneh WA.Unplanned surgical excision of tumors of the foot and ankle[J].Cancer Control,2001,8(3):262-268.
- [7]Selch MT,Kopald KH,Ferreiro GA,et al.Limb salvage therapy for soft tissue sarcomas of the foot[J].Int J Radiat Oncol Biol Phys,1990,19(1):41-48.
- [8]王晋.下肢远端恶性肿瘤的保肢治疗[J].中国骨肿瘤骨病,2006,5(2):73-79.
- [9]Lin PP,Guzel VB,Pisters PW,et al.Surgical management of softtissue sarcomas of the hand and foot[J].Cancer,2002,95(4):852-861.
- [10]Ozaki T,Hillman A,Lindner N.Surgical treatment of bone sarcomas of the fibula:analysis of 19 cases[J].Arch Orthop Trauma Surg,1997,116(8):475-479.
- [11]Casadei R,Ruggieri P,Giuseppe T,et al.Ankle resection arthrodesis in patients with bone tumors[J].Foot Ankle Int,1994,15(5):242-249.
- [12]Langstein HN,Chang DW,Miller MJ,et al.Limb salvage for softtissue malignancies of the foot:an evaluation of free-tissue transfer[J].Plast Reconstr Surg,2002,109(1):152-159.
- [13]Papagelopoulos PJ,Mavrogenis AF,Badekas A,et al.Foot malignancies:a multidisciplinary approach[J].Foot Ankle Clin,2003,8(4):751-763.
- [14]Chou LB,Malawer MM.Analysis of surgical treatment of 33 foot and ankle tumors[J].Foot Ankle Int,1994,15(4):175-181.
- [15]zger H,Eralp L,Türker M,et al.Surgical treatment of malignant tumors of the foot and ankle[J].Int J Clin Oncol,2005,10(2):127-132.