余伟波;梁德;江晓兵;叶林强;姚珍松;

• 1:广州中医药大学第一附属医院脊柱骨科
• 2:广州中医药大学第一临床医学院

摘要(Abstract)：

[目的]分析骨质疏松椎体压缩骨折(osteoporotic vertebral compression fractures,OVCFs)中椎体内裂隙(intravertebral vacuum cleft,IVC)发病率及其在伤椎内位置特点,并比较不同位置IVC对经皮椎体强化术治疗有IVC的OVCFs治疗效果影响差异。[方法]共有52例单节段并位于胸腰区域(T_(11)~L_1)有IVC的OVCFs患者纳入回顾性研究,随访时间均超过两年。根据IVC在伤椎内的位置特点,将所有患者分为三组:IVC偏上组、IVC偏下组和IVC达到上下终板组。三组组间及组内相应的放射学和临床参数在术前、术后(即时、术后1年、术后2年)分别比较。[结果]三组患者术前基值差异均无统计学意义,具有可比性。三组患者术后即时的椎体高度及后凸角均显著矫正;三组术后即时放射学及临床参数差异无统计学意义。在术后1、2年随访期间内,三组患者椎体高度及后凸角角均进展性加重,尤以IVC偏下组为最重,其次是IVC偏上组。三组在伤椎复位率及复位角差异无统计学意义(P<0.05);IVC偏下组2年内的高度及后凸丢失率显著超过其他两组(P<0.05)。[结论]经皮椎体强化术起初对于所有IVC的OVCFs患者有效。然而,在后期随访中IVC偏下组更易出现严重的椎体再塌陷及后凸畸形,因此建议术后需要严密的观察及随访。

关键词(KeyWords)： 椎体内裂隙;骨质疏松椎体压缩骨折;经皮椎体强化术;强化椎

Abstract:

Keywords:

基金项目(Foundation): 广东省卫生厅医学科研基金项目(编号:2014B2014175);; 卫生部医药卫生科技发展研究中心资助课题(编号:W2014ZT256;W2012ZT0)

作者(Author): 余伟波;梁德;江晓兵;叶林强;姚珍松;

Email:

DOI:

参考文献(References)：

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