罗栩伟;冯刚;

• 1:四川南充市中心医院骨科
• 2:川北医学院第二临床医学院
• 3:川北医学院组织工程与干细胞研究所

摘要(Abstract)：

<正>长年劳损、慢性疾病或脊柱外伤等造成的椎间盘退行性变疾病(intervertebral disc degeneration disease,IDD)为临床的常见病和多发病,是引起下腰痛的主要病因。传统的治疗方法包括非手术保守治疗和手术治疗,虽然在一定程度上可缓解临床症状,但不能解决根本问题,还会引起相应的并发症。椎间盘细胞自我修复能力也极为有限,许多促进其再生和修复的方法不太令人满意。近年来研究发现,生长分化因子5(growth and differentiation factor-5,GDF5)除了参与调

关键词(KeyWords)： 生长分化因子5;椎间盘退行性变;蛋白多糖;Ⅱ型胶原

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金(编号:30872614和编号:81071270);; 四川省科技支撑计划项目(编号:2008SZ0103);; 四川省杰出青年学科带头人资助计划(编号:2009-05-396);; 川北医学院苗圃基金(编号:MP-09A-06)

作者(Author): 罗栩伟;冯刚;

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