球囊后凸成形术治疗骨质疏松椎体压缩性骨折
王宇翔;徐海栋;赵建宁;
摘要(Abstract)：
[目的]探讨椎体球囊后凸成形术对骨质疏松椎体压缩性骨折的治疗效果。[方法]对2018年3月～2018年11月因椎体压缩性骨折至本院就诊、行"椎体球囊后凸成形术"的患者进行随访,记录其术前、术后的疼痛评分和功能评分并进行对比,评估其手术疗效。[结果]所有患者均顺利完成手术,手术时间平均(40.91±4.63) ml,术中出血量平均(31.83±6.04) ml,平均住院(2.41±0.62) d,未出现神经根损伤、大出血等术中并发症。术后患者VAS评分及ODI评分均明显降低,差异有统计学意义(P<0.05)。随访3个月期间,所有患者均未出现骨水泥移位、骨水泥栓塞等并发症。1例患者术后1个月出现伤椎邻椎骨折,再次行椎体成形手术治疗。[结论]椎体球囊后凸成形术能够有效缓解椎体压缩性骨折患者的疼痛,提高生活质量。
关键词(KeyWords)： 椎体球囊后凸成形术;椎体压缩性骨折;骨质疏松
基金项目(Foundation): 国家自然科学基金青年科学基金项目（编号：81501925）;; 中国博士后科学基金项目（编号：2016M593038）
作者(Author): 王宇翔;徐海栋;赵建宁;
Email:
DOI:
参考文献(References)：
- [1] Wei D, Jung J, Yang H, et al. Nanotechnology treatment options for osteoporosis and its corresponding consequences[J]. Curr Osteoporosis Rep, 2016, 5:239-247.
- [2] Riggs BL, Melton LR. The worldwide problem of osteoporosis:insights afforded by epidemiology[J]. Bone, 1995, 17(5):505-511.
- [3] Venmans A, Klazen CA, Lohle PN, et al. Natural history of pain in patients with conservatively treated osteoporotic vertebral compression fractures:results from VERTOS II[J]. AJNR Am J Neuroradiol, 2012, 33(3):519-521.
- [4] Galibert P, Deramond H, Rosat P, et al. Preliminary note on the treatment of vertebral angioma by percutaneous acrylic vertebroplasty[J]. Neurochirurgie, 1987, 33(2):166-168.
- [5] Kaemmerlen P, Thiesse P, Bouvard H, et al. Percutaneous vertebroplasty in the treatment of metastases. Technic and results[J]. J Radiol, 1989, 70(10):557-562.
- [6] Bonnard E, Foti P, Kastler A, et al. Percutaneous vertebroplasty under local anaesthesia:feasibility regarding patients'experience[J]. Eur Radiol, 2017, 27(4):1512-1516.
- [7] Barr JD, Barr MS, Lemley TJ, et al. Percutaneous vertebroplasty for pain relief and spinal stabilization[J]. Spine(Phila Pa 1976),2000, 25(22):2968-2969.
- [8] Kim YC, Kim YH, Ha KY. Pathomechanism of intravertebral clefts in osteoporotic compression fractures of the spine[J]. Spine J,2014, 14(4):659-666.
- [9] Do HM, Jensen ME, Marx WF, et al. Percutaneous vertebroplasty in vertebral osteonecrosis(Kummell's spondylitis)[J]. Neurosurgical Focus, 1999, 7(1):e2.
- [10] Suk SI, Kim JH, Lee SM, et al. Anterior-posterior surgery versus posterior closing wedge osteotomy in posttraumatic kyphosis with neurologic compromised osteoporotic fracture[J]. Spine(Phila Pa1976), 2003, 28(18):2170-2175.
- [11] Arabmotlagh M, Rickert M, Lukas A, et al. Small cavity creation in the vertebral body reduces the rate of cement leakage during vertebroplasty[J]. J Orthop Res, 2017, 35(1):154-159.
- [12] Butscheidt S, Rolvien T, Ritter J, et al. Pulmonary cement embolism is not associated with the cause of death in a post-mortem cohort of cement-augmented interventions in the spine[J]. Eur Spine J, 2018, 27(10):2593-2601.
- [13] Chen YC, Lin WC. Can anti-osteoporotic therapy reduce adjacent fracture in magnetic resonance imaging-proven acute osteoporotic vertebral fractures[J]. BMC Musculoskelet Disord, 2016, 17(5):151.
- [14] Khosla A, Diehn FE, Rad AE, et al. Neither subendplate cement deposition nor cement leakage into the disk space during vertebroplasty significantly affects patient outcomes[J]. Radiology, 2012,264(1):180-186.
- [15] Chen CY, Cheng WE, Lin CH, et al. Tadpoles in the lungs. Cement pulmonary embolism complicating vertebroplasty of spinal metastasis[J]. Am J Respir Crit Care Med, 2014, 190(3):340-341.
- [16] Lu K, Liang CL, Hsieh CH, et al. Risk factors of subsequent vertebral compression fractures after vertebroplasty[J]. Pain Medicine,2012, 13(3):376-382.
- [17] Zafeiris CP, Lyritis GP, Papaioannou NA, et al. Hypovitaminosis d as a risk factor of subsequent vertebral fractures after kyphoplasty[J]. Spine J, 2012, 12(4):304-312.